Kosin Medical Journal

Original article

The Characteristics of Staphylococcal Scalded Skin Syndrome in Atopic Dermatitis: Woo jin Jung, Sung Won Kim, Yoon Ha Hwang; Kosin Med J. 2019;34(2):138-145. Published online December 31, 2019; DOI: https://doi.org/10.7180/kmj.2019.34.2.138

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Abstract PDF PubReader ePub: Objectives
Staphylococcal scalded skin syndrome (4S), a blistering dermatosis caused by exfoliative toxins from Staphylococcus aureus, occurs frequently in patients with atopic dermatitis (AD). However, association between 4S and AD has not rarely been reported. We investigated the characteristics of 4S according to AD status.
Methods
The study included 146 children with 4S who visited Busan St. Mary's Hospital from 2007–2018. Clinical features were analyzed from medical records and pictures, and 4S was classified as localized or generalized. We also retrospectively investigated the preceding conditions and test results related to AD.
Results
Among 146 patients with 4S, median age was 2.0 years, and 35 (24.0%) had AD. Since 2007, the incidence of both 4S and AD have increased, without obvious seasonal patterns. Generalized and localized disease occurred in 90 and 56 patients, respectively. Twenty-four of 35 patients with AD (68.6%) and 32 of 111 (28.8%) without AD had localized disease. Significant differences were observed between the groups (P = 0.000). Among those with AD, the most common preceding condition was skin infection or unknown (45.2%); however, respiratory disease was the most common (47.9%) among patients without AD. Eosinophil levels were higher in the AD group (P = 0.002), and there were no statistically significant differences in total immunoglobulin E (IgE), Dermatophagoides farinae (Df IgE), egg-white IgE, and culture results between the groups.
Conclusions
Localized 4S frequently occurred without preceding conditions in children with AD and usually arose from skin infection compared to generalized 4S.

Case reports

A Case of an Infant Diagnosed with Cow's Milk Allergy and Concurrent Meat Allergy via ImmunoCAP ISAC®: So Yoon Jo, Chan Ho Lee, Sung Won Kim, Yoon Ha Hwang; Kosin Med J. 2019;34(1):72-77. Published online June 30, 2019; DOI: https://doi.org/10.7180/kmj.2019.34.1.72

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Approximately 13–20% of infants with milk allergies concurrently exhibit beef allergies. Here, we report a 24-month-old infant who exhibited both pork and beef allergies, concurrently with a milk allergy. The infant's laboratory test results were: 3.73 ISU-E (ISAC standardized unit for IgE) for cow milk β-lactoglobulin, 23.8 ISU-E for casein, 12.8 ISU-E for cow milk Bos d 6 of serum albumin, and 4.85 ISU-E for cat Fel d 2. This case report summarizes an infant patient diagnosed with a meat allergy that was associated with cow's milk allergy, using ImmunoCAP ISAC®. Not only ImmunoCAP ISAC® but also immunocap can be used to diagnose milk allergy and meat allergy at the same time, immunocap testing for component antigen is rare. ImmunoCAP ISAC® is used to diagnose these allergies in our case study, as it has advantage that only 1ml of blood is needed to run various component antigen tests.

Citations

Citations to this article as recorded by

Preparation, Identification and Application of β-Lactoglobulin Hydrolysates with Oral Immune Tolerance
Linghan Tian, Qianqian Zhang, Yanjun Cong, Wenjie Yan
Foods.2023; 12(2): 307. CrossRef
Benefits, perceived and actual risks and barriers to egg consumption in low- and middle-income countries
Chhavi Tiwari, Mulubrhan Balehegn, Adegbola T. Adesogan, Sarah L. McKune
Frontiers in Animal Science.2023;[Epub] CrossRef

Mycoplasma Pneumoniae-Associated Necrotizing Pneumonia in Children: a case-report: Chan ho Lee, So Yoon Jo, Keon Woo Na, Sung Won Kim, Yoon Ha Hwang; Kosin Med J. 2019;34(1):57-64. Published online June 30, 2019; DOI: https://doi.org/10.7180/kmj.2019.34.1.57

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Abstract PDF PubReader ePub

Mycoplasma pneumoniae is the most common bacterial strain causing atypical pneumonia in children and adolencents. Although it is known to cause mild symptoms, it can also cause severe pulmonary or extrapulmonary complications in rare cases. Necrotizing pneumonia (NP) is often reported as a complication of Streptococcus pneumoniae and is very rarely caused by M. pneumoniae. We report a case in which a 5-year-old boy was diagnosed with lobar pneumonia with symptoms that aggravated even with macrolide antibiotic treatment. Anti-mycoplasma pneumoniae Ig-M test yielded high values, and direct polymerase chain reaction results were also positive. NP caused by M. pneumoniae was confirmed on computed tomography. After treatment involving tosufloxacin and systemic steroid, the lesion decreased in size and improved gradually when followed-up for more than 1 year. The patient did not have any predisposing or risk factors for NP.

Citations

Citations to this article as recorded by

Cavitatory necrotising pneumonia with extrapulmonary multi-systemic involvement — a rare presentation of macrolide-resistant Mycoplasma pneumoniae
Namitha Mohan, Vishal Dnyaneshwar Sawant, Alpana Kondekar
The Egyptian Journal of Internal Medicine.2023;[Epub] CrossRef

A 14-year-old boy with endobronchial carcinoid tumor presenting with asthma: Yunmo Gu, Youngjin Hwang, Sung Won Kim; Kosin Med J. 2017;32(2):221-226. Published online January 19, 2017; DOI: https://doi.org/10.7180/kmj.2017.32.2.221

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Abstract PDF PubReader ePub: Introduction
Bronchial carcinoid tumors seldom occur in children, sometimes mistaken for a minor disease and diagnosed slowly. Materials and Methods: We report on a patient who diagnose tumors slowly because confused with asthma.
Results
This case describes a 14-year-old boy, presenting with asthma-like symptoms throughout 3 years. He was treated as asthma but wax and wane. Chest x-ray showed an hyperlucent left lung, so we rechecked high resolution computed tomography (HRCT) for unilateral hyperinflation diseases diagnosis. It was found 1×1㎝ nodule in left main bronchus. We did bronchoscopy and discovered a round mass in the left bronchus, 2∼3㎝ away from carina. In the biopsy, it was bronchial carcinoid tumor, so we resected tumor.
Discussion
Because symptoms of bronchial carcinoid tumors are various, it can often be misdiagnosed firstly. It is confused with asthma, pneumonia and foreign body. An additional examination were necessary when respiratory symptoms persist.

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